The Global Head of Data Science is a strategic leadership role responsible for overseeing computational science, biostatistics and data management functions bringing computational solutions to research and development. This leader will design the data roadmap to accelerate drug discovery, optimize clinical trials, regulatory submissions, and, as applicable, accelerate development processes using AI and machine learning (ML). The Head of Data Science will be part of a highly collaborative and cross-functional Development Leadership Team driving the full life-cycle development of our antibody-drug conjugates (ADCs) global clinical trials. They will play an important role in defining and executing the overall product development strategy for Tubulis.
This position will report to the Chief Medical Officer and be based in Boston, MA or possible remote opportunities within other locations within the U.S.
- Lead, oversee and execute biostatistics, statistical programming, data management, and data science activities for preclinical and clinical studies across the global portfolio.
- Develop and communicate the vision and mission of the biostatistics and data sciences platform, driving strategic plans to achieve organizational goals.
- Partner with leaders across biology, chemistry, clinical development, and IT to integrate data-driven insights into the end-to-end drug development lifecycle.
- Oversee the creation of predictive models for clinical outcomes, efficacy, safety profiles, and asset prioritization using multi-modal data.
- Ensure appropriate design, collection, management, statistical analysis, and reporting of clinical study data, supporting the entire study data lifecycle.
- Establish robust data management frameworks ensuring data quality, integrity, and security while adhering to global regulatory standards like GxP, HIPAA, and FDA 21 CFR Part 11.
- Drive standardization, harmonization, and process optimization to increase productivity, quality, and reduce cycle times and costs.
- Allocate resources globally to deliver high-quality, timely outcomes aligned with study and project objectives.
- Foster innovative scientific methodologies and the adoption of new technologies for state-of-the-art statistical analyses and data reporting.
- Establish and maintain frameworks for regulatory (GxP) compliance and consistency in statistical planning, analysis, and data management tasks.
- Liaise with regulatory agencies, academic opinion leaders, and cross-functional teams to ensure scientific rigor and regulatory alignment.
- Contribute to the development and execution of outsourcing strategies to optimize operations.
- PhD or equivalent in Computational Biology, Bioinformatics, Computer Science, Biostatistics, or a related scientific/quantitative field.
- Extensive experience (10+ years) in biostatistics and data management within a pharmaceutical, biotech and academic environment.
- Proven leadership experience managing and building diverse and high-performing global teams.
- Deep knowledge of scientific decision processes integral to research and regulatory submissions.
- Experience in leading preclinical and clinical research projects and familiarity with regulatory requirements and clinical data lifecycle.
- Must have experience working within Oncology clinical trials.
- Experience supporting pivotal Phase III programs and proven statistical expertise in statistical planning, study design, data.
- Ability to develop vision and strategy for biostatistics and data science functions.
- Ability to foster innovation and continuous improvement in biostatistics and data management process.
- Proactive and independent thinker and strong team player.
- Strong organizational, communication, and personnel management skills.
- Entrepreneurial and problem-solving mindset.
At Tubulis, curiosity and innovation drive us to transform cancer treatment. We are a fast-growing biotech where science meets passion—and where you have the chance to grow with us.
Impact that matters: Contribute to breakthrough therapies.- Global mindset: Work in an international, diverse team.
- Grow & thrive: Develop your career in a supportive, fast-moving environment.
- Innovation every day: Push boundaries with cutting-edge science.
At Tubulis, your ideas matter, your growth matters—and together, we make a difference.
The development of novel, effective and safe therapies for the treatment of cancer is one of the main challenges for modern medicine. We want to drive this process forward. The main goal of Tubulis is to become a leading company in the field of targeted therapeutics and antibody-drug conjugates (ADCs). With a strong team, our own technologies and innovative therapeutic concepts, we are ushering in a new era in the ongoing fight against cancer and share the vision of helping patients world-wide. Be part of a multidisciplinary and focused team, that works towards getting novel promising ADCs to patients with solid and hematological cancers.
