Are you ready to lead the charge in transforming cancer treatment? As the Director, Cancer Vaccines Technologies in Early Vaccines and Immune Therapies. Here you will be responsible for leading efforts to develop and deliver a portfolio of the new modalities to train the immune system to recognize and eliminate malignant cells. The Director will build on previous experience in cancer vaccines to exploit various vaccine platforms to drive long-lived, robust immune responses to prevent, treat, and drive long-lived surveillance of tumors. Building on the current state of the field, the Director will be tasked with developing preclinical strategy, guiding antigen discovery, supporting vaccine design, and developing combinatorial approaches to amplify clinical impact. The candidate will lead work across cross-functional teams to build programs. The director will be responsible for driving collaboration and influencing internal stakeholders. In addition, the Director will develop and build a cutting-edge portfolio of intellectual property— guiding a team that fosters high-performance and innovation; building capabilities across immunology, oncology, and translational

sciences; and establishing clear operating mechanisms to accelerate decision-making and delivery

Accountabilities

Develop a preclinical pipeline for the design, testing, and delivery of cancer vaccine programs
Implement a strategy to explore multiple vaccine modalities to train immunity to eliminate tumors
Create an approach to evaluate combinatorial modalities to maximize control, clearance, and surveillance
Develop a strategy to drive target discovery and evaluation
Work with cross-disciplinary teams to guide iterative antigen design and preclinical evaluation
Establish strategic relationships across the organization and functions
Build animal models for rapid evaluation of emerging modalities
Support the development of a regulatory strategy to translate programs to clinic
Create and foster effective relationships with senior and executive stakeholders in Research, Bioprocess Development, Clinical and Translational Medicine and Global Project Teams to ensure alignment across functions
Pioneer AI based strategies to accelerate the pace of innovation at all levels of research
Collaborate and guide the evaluation of novel business development opportunities
Communicate results internally and externally, as well as their associated risks, uncertainties and limitations
Define the training standards for junior colleagues in line with best practices and principles

Essential Skills/Experience

PhD or equivalent in immunology, oncology, molecular biology, biochemistry or a related discipline with 10+ years industry experience
Proven experience developing novel immunological approaches to deploy immunity to fight tumors
Proven experience with immune profiling, tumor modeling, systems biology, and/or immune oncology
Experience working in a cross-functional team to maximize expertise and accelerate success
Experience developing and implementing novel methods to support vaccine development
Experience supporting or leading interdisciplinary vaccine discovery or development programs
Proven experience leading and managing junior colleagues
Proven experience developing and controlling budgets
Excellent written and verbal communication, business analysis, and consultancy skills

Desirable Skills/Experience

PhD or MD degree in immune-oncology
Comfortable working with and leading lab and computational scientists across disciplines
Familiarity with animal tumor models
Proven track record of publishing relevant results and tools in peer-reviewed journals, conferences, and other scientific proceedings
Experience in life sciences and healthcare
Experience in novel methods development and application
Experience in a complex global organization

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca is at the forefront of medical innovation, transforming healthcare with energy and drive. Our commitment to addressing pandemic preparedness ensures our products reach millions globally. We thrive on collaboration, investing in groundbreaking partnerships that lead to essential breakthroughs. Our diverse community empowers everyone to share ideas, challenging norms to push scientific boundaries. With a people-centric approach, we make exceptional breakthroughs that enhance lives worldwide.

Ready to make a difference? Apply now to join our dynamic team!

The annual base pay ranges from 172,672.00 - 259,008.00. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

AstraZeneca

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Director, Cancer Vaccines Technologies