Postdoctoral Fellow in Bioinformatics – Chemoproteomics & Cancer Functional Genomics
Position Overview
A postdoctoral fellow position is available for a highly motivated scientist with expertise in bioinformatics, chemoproteomics, and functional genomics. The successful candidate will participate in research projects leveraging large-scale chemoproteomics datasets, integrating these with public cancer genomics resources, and mining CRISPR screening data to advance cancer biology and therapeutic discovery.
Key Responsibilities:
- Analyze and integrate high-dimensional chemoproteomics datasets with multi-omotic data (e.g., genomics, transcriptomics, proteomics) from public repositories such as DepMap and TCGA
- Develop, implement, and maintain robust computational pipelines in R and other programming languages (e.g., Python) for data processing, statistical analysis, and visualization
- Mine and interpret large-scale CRISPR screening datasets to identify novel cancer dependencies and therapeutic targets, utilizing resources such as DepMap and published CRISPR screens
- Collaborate with interdisciplinary teams of biologists, chemists, and clinicians to design and execute integrative studies, and contribute to the functional validation of computational predictions
- Present research findings at internal meetings and national/international conferences; publish results in high-impact journals
- Mentor junior researchers and contribute to grant writing and manuscript preparation
Required Qualifications:
- PhD in Bioinformatics, Computational Biology, Cancer Biology, Genomics, or a related field is required
- Demonstrated expertise in R and proficiency in other programming languages (e.g., Python)
- Experience working with and mining large public cancer genomics databases, such as DepMap and TCGA
- Proven track record in analyzing and integrating chemoproteomics and/or functional genomics datasets, especially CRISPR screening data
- Strong understanding of statistics and machine learning concepts as applied to biological data
- Excellent written and verbal communication skills, with a history of publishing in peer-reviewed journals
- Ability to work independently and collaboratively in a multidisciplinary research environment
Preferred Qualifications
- Experience with drug development and/or chemistry
- Familiarity with AI/ML approaches for biological data analysis.
- Prior experience in cancer research or translational bioinformatics
Application Instructions:
Interested applicants should submit a CV, a cover letter outlining research experience and interests, and contact information for three references. Applications will be reviewed on a rolling basis.
Location: H. Lee Moffitt Cancer Center & Research Institute · Clinical Science Lab
Schedule: Full Time, Day Shift, variable
