Job Description The Senior Bioinformatics Analyst is responsible for designing, developing, and operating structured databases and analysis pipelines to optimize usage and accessibility. Manages data integration and coordinates other efforts related to infrastructure with minimal supervision.
The Northcott Lab within the Center of Excellence in Neuro-Oncology Sciences (CENOS) is seeking a highly motivated Senior Bioinformatics Analyst. The CENOS is a collaborative translational research program with a mission to improve survival and morbidity for children with brain tumors. Through application of cutting-edge molecular approaches to unique and data-rich cohorts, members of this program are efficiently translating laboratory findings into clinical practice and treatment innovations.
The successful candidate will contribute to the management, usage, and accessibility of unprecedented multi-'omics datasets obtained from children with malignant brain cancer. Through application of structured/unstructured databases, storage and integration of large multi-modal datasets, including bulk, single-cell, and spatial profiles, we aim to make novel insights with real-world clinical implications.
The candidate will work closely with bioinformatics personnel within the CENOS to play a role in exciting collaborations, both within St. Jude and with prominent external collaborators. A deep understanding of database development, maintenance, and optimization are essential for this position. The successful recruit must have the capacity to execute proficient data storage, management, and integration strategies and troubleshoot independently, communicate effectively with the PI and collaborators across diverse disciplines, and thrive in a highly collaborative team environment.
The ideal candidate should have:
- A Master's degrees in computer science, bioinformatics, computational biology, and/or data science.
- Minimum experience: 1+ years of relevant experience
- Experience in the development, implementation, and maintenance of relevant databases or data warehouse.
- Experience developing prototypes for cloud portals and visualization tools; programs for the analysis of data within databases.
- Experience developing web services to query the database.
- Experience with genomic datasets (e.g. whole-genome/exome sequencing, RNA-seq, ATAC-seq, ChIP-seq/CUT&RUN, Hi-C, DNA methylation, single-cell/nucleus RNA-seq, spatial transcriptomics, and quantitative proteomics)
- Experience in programming querying languages
- Experience in at least one programming or scripting language, preferred
Minimum Education and/or Training:
- Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
- Master's degree preferred.
Minimum Experience:
- Minimum Requirement: 4+ years of relevant experience required.
- Experience Exception: Master's degree and 1+ years of relevant experience.
- Experience in at least one programming or scripting language and at least one statistical package, with R preferred.
Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $78,000 - $139,360 per year for the role of Senior Bioinformatics Analyst - Center of Excellence in Neuro-Oncology Sciences.
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