JOB SUMMARY:

The Research Tech V will work under the supervision of Scientist in the Ferrington Lab at Doheny Eye Institute investigating mechanisms and therapeutic strategies in age-related macular degeneration. This position will collaborate with principal investigator and other laboratory researchers to plan, design, and conduct highly technical and complex research projects. Research in Ferrington lab focuses on mechanisms that link genetic risk factors to mitochondrial dysfunction in RPE cells.

DUTIES AND RESPONSIBILITIES :

1. Plan and conduct highly technical and complex research projects: Design and conducts research experiments in accordance with laboratory and safety protocols, laboratory procedures and techniques, including but not limited to: (Percentage of time: 70%)

Preparing experimental reagents and buffers
cell culture from iPSC or iPSC-RPE and cell-based assays
Seahorse assays
Flow cytometry
Western blotting
Immunostaining/Histology
ELISA
Quantitative PCR
Bioinformatics analysis

2. Experiment Design: Collaborate with Scientist and Principal Investigator and other research personnel to plan and design experiment. Design methods for new research projects. Review progress and discuss with Principal Investigator.

3. Laboratory Procedure and Policy Development: Contribute to the development and implementation of laboratory procedures and policies. Coordinates and organizes laboratory: monitoring consumable stocks, freezer organization and data storage (Percentage of time: 15%)

4. Maintains accurate records of procedures used to conduct experiments. Provide data summaries for review by supervisor (Percentage of time: 10%)

5. Provides input and updates on progress of research and makes recommendations for modification as appropriate. (Percentage of time: 5%)

6. Perform all tasks in a safe and timely manner in compliance with safety policies and according to hazardous materials regulations; maintains a neat workstation and environment. (Percentage of time: ongoing)

7. Perform special projects or other related work as required or requested. (Percentage of time: Ongoing)

SUPERVISION:

Function under the direction of the Doheny scientist.

EDUCATIONAL EXPERIENCE, TRAINING :

1. Education

Bachelor’s/Master’s degree in biological science or related science required.
Combined education and/or experience may be used as substitute for minimum education.

2. Experience

5 - 8 years research/lab experience.
Experience in biological science-related field required.
Lab experience working in cell biology, molecular biology and biochemistry required.

3. Abilities and Characteristics

Proficient English communication skills – both verbal and written.
Ability to work on simultaneous projects and effectively prioritize work.
Detail oriented and excellent analytical skills.
Ability to work independently and be self motivated.
Good teaching ability.
Ability to carry out work assigned according to research protocol.
Attention to detail, excellent organizational and record keeping skills.
Strong aseptic technique; mammalian cell culture (thawing, passaging, cryopreservation, contamination prevention)
Accurate bench skills: pipetting, solution/reagent preparation, buffer making, calculations, dilution series
Meticulous documentation (electronic lab notebook), labeling, sample tracking, inventory
Reproducibility mindset: follows SOPs, maintains consistent technique, documents deviations
Safety and compliance: BSL-2 practices, chemical hygiene, waste disposal
Organized and reliable: prioritizes tasks, meets deadlines, maintains clean shared spaces
Collaborative: communicates clearly with PI and lab members; supports multiple projects
Demonstrated ability to follow SOPs and maintain high standards of lab safety and compliance
Bioinformatics skills and techniques (such as R and Python)
Routine analysis and interpretation of research data
Motivated learner with a proactive approach to troubleshooting and improving workflows

Job Type: Full-time

Pay: $45,000.00 - $60,000.00 per year

Benefits:

Dental insurance
Employee assistance program
Flexible spending account
Health insurance
Life insurance
Paid time off
Retirement plan
Vision insurance

People with a criminal record are encouraged to apply

Work Location: In person

Doheny Eye Institute

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Research Technician V